AN UNBIASED VIEW OF CONOLIDINE ALKALOID FOR CHRONIC PAIN

Most lately, it's been discovered that conolidine and the above derivatives act within the atypical chemokine receptor 3 (ACKR3. Expressed in similar places as classical opioid receptors, it binds to some big selection of endogenous opioids. Unlike most opioid receptors, this receptor acts as a scavenger and will not activate a second messenger met